Bologna is home to leading onco-hematologists and specialists in hematologic malignancies, blood disorders, bone marrow transplantation, and cellular therapies. The top onco-hematologists in Bologna manage diseases such as leukemia (acute and chronic), lymphomas, myeloma, myelodysplastic and myeloproliferative syndromes, and are also specialized in therapies such as stem cell transplantation, immunotherapy including CAR-T, and advanced diagnostics (flow cytometry, molecular profiling, bone marrow biopsy). The Hematology Unit at the Istituto “L. & A. Seràgnoli” in the Policlinico Sant’Orsola-Malpighi is a reference center for adult onco-hematology, combining patient care, laboratory work, and clinical trials for innovation in blood cancer treatment.
Onco-hematologic disease burden in Italy is significant: blood cancers represent a substantial proportion of new cancer cases each year, and therapies such as transplantation and CAR-T are growing in use. In Bologna, the Seràgnoli Institute is among the top centers nationally, performing many allogeneic and autologous stem cell transplants. The center is JACIE-accredited for adult bone marrow transplantation and cellular therapies. It has treated over 200 patients with CAR-T therapies in recent years, across lymphoma, myeloma, and select leukemias. Bologna’s Hematology reports high publication output, high research citation metrics, and excellent outcomes in transplant survival compared to regional and national averages. Patients benefit from early diagnosis, access to clinical trials, strong supportive care, and integrated laboratory-diagnostic services.
If you’re seeking treatment for an oncologic-hematologic disease, Bologna offers advantages that combine medical excellence, research, and patient care.
➤ Depth of clinical and translational research – Leading onco-hematologists in Bologna are active in phase I-III trials, molecular diagnostics, immunotherapy, and personalized medicine.
➤ Comprehensive treatment portfolio – From diagnosis (bone marrow biopsy, molecular and cytogenetic profiling), through chemotherapy, stem cell transplantation (autologous, allogeneic), to CAR-T and cellular therapy.
➤ Accreditation & safety standards – The Seràgnoli Institute is JACIE-accredited for adult stem cell transplantation, ensuring high quality in transplant programs and cellular therapy protocols.
➤ High case volume & outcome consistency – High numbers of transplants, lymphoma and myeloma treatments, and novel therapies mean teams have strong experience managing complex cases.
➤ Patient-centered multidisciplinary care – Hematologists, oncologists, pathologists, transplant physicians, immunologists, nursing and lab specialists work together with psycho-social support and patient navigation.
➤ Public & private care balance – Treatments are available under the Italian National Health Service and via private practice/ libero professionale settings, offering options for speed, comfort, and cost flexibility.
Here are five prominent onco-hematology specialists in Bologna, with what makes them stand out and their specialties.
Prof. Michele Cavo
Prof. Cavo is Director of the Hematology Unit “Seràgnoli” and a full professor at the University of Bologna. He has led many phase II-III studies in myeloma, published hundreds of peer-reviewed articles, and contributed significantly to the development of treatment protocols that improve survival. Patients praise his clarity, dedication, and availability in consulting on complex cases.
Prof. Pier Luigi Zinzani
Prof. Zinzani heads the Lymphoma Unit at the Seràgnoli Institute. He has directed numerous national and international multicentre trials, is well known for integrating diagnostic precision (molecular and immunophenotypic) into treatment selection, and for delivering individualized therapy plans.
Dott. SSA Francesca Bonifazi
Dr. Bonifazi is Director of the “Trapianto e Terapie Cellulari Avanzate” program at the Seràgnoli Institute. She coordinates patient workups for transplant, manages donor selection, oversees cellular processing labs, and follows patients post-transplant or post-CAR-T. Her work is often cited in relation to improving transplant safety and outcomes in harder cases.
Dr. Mario Arpinati
Dr. Arpinati works in the transplantation and advanced cellular therapy team. He is involved in patient management for leukemia and other blood cancers, especially for transplant candidates, and supports research in optimizing therapy regimens and reducing transplant-related toxicity.
Prof. Fausto Castagnetti
Prof. Castagnetti is part of the Seràgnoli team, known for diagnostic excellence and patient care. He is involved in managing outpatient follow-up for onco-hematology patients, especially those with lymphomas and myeloma, ensuring long-term surveillance, managing relapse strategies, and improving quality of life.
Choosing an onco-hematologist is critical to treatment success, prognosis, and quality of life. Best Clinic Abroad helps you throughout the journey with personalized and practical support.
We assess your specific diagnosis (type of leukemia, lymphoma, myeloma, or blood disorder), your previous treatments, genetic/molecular test results, age, treatment goals, and preferences to match you with the most appropriate specialist. We also help you verify your diagnostic reports and lab results to ensure nothing is overlooked.
➤ Personalized doctor matching – Based on disease type, transplant needs, cellular therapy, immunotherapy, or standard hematologic treatment, we suggest specialists whose expertise aligns closely with your condition.
➤ Coordination of diagnostics & second opinion – We help arrange molecular profiling, cytogenetics, imaging, bone marrow biopsy reviews, and second opinions if needed to guide treatment planning.
➤ Appointment scheduling & hospital admission support – We manage consultation slots, pre-transplant assessments, donor or cell processing preparation, and hospital logistics for transplant or CAR-T therapy.
➤ Clear cost & financial plan – We provide detailed estimates for consultations, chemotherapy, transplant or CAR-T, hospital stay, cellular therapy labs, and follow-ups so there are no surprises.
➤ Assistance for international patients – Support with travel, accommodation, interpreters, visa process, and navigating the choice between public and private care.
➤ Post-treatment follow-up & supportive care – After therapy, we help you access follow-ups, manage side effects, monitor minimal residual disease, nutrition, psychosocial support, and long-term health maintenance.
With Best Clinic Abroad, you gain access to Bologna’s top onco-hematology specialists, advanced treatment centers, and a partner committed to your safety, outcomes, and comfort. You will be supported not only medically but also personally so that your onco-hematology journey is as clear, efficient, and hopeful as possible.
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