
The Cancer & Hematology Unit (ORPHé) at Pitié‑Salpêtrière offers integrated care in medical oncology, hematology, and radiotherapy. Serving as a national reference center, it specializes in complex hematological malignancies, such as chronic lymphocytic leukemia, Waldenström’s disease, central nervous system lymphomas, and transplant-associated cancers while driving rare-cancer networks like K‑VIROGREF and the National Family Lymphoid Hemopathies Register. Equipped with a clinical hematopoietic stem cell transplantation unit and a pharmacy specialized in onco-hematology (UPCO), the department conducts over 5,000 therapeutic sessions annually, including CAR-T cell therapy, photopheresis, and plasmapheresis. It collaborates across specialties from radiotherapy to palliative care and offers rapid patient pathways, early-phase clinical trials, and strong research integration, delivering a structured, multidisciplinary approach to cancer treatment.
Cardiology & Cardiovascular Surgery at Hôpital Pitié‑Salpêtrière
Hôpital Pitié‑Salpêtrière’s Heart and Vascular Center ranks among the top cardiac care facilities in Europe, blending clinical precision with interdisciplinary expertise. The department treats adults facing complex cardiovascular conditions, ranging from coronary artery disease and heart failure to congenital heart defects and aortic aneurysms. A close-knit team of interventional cardiologists, cardiac surgeons, electrophysiologists, and intensivists works seamlessly in a modern setting equipped with five catheter labs (including a hybrid operating theatre) and fully integrated ICU services.
✔ Advanced Interventions & Imaging – Procedures include angioplasty, stenting, TAVI, valve repair/replacement, ECMO, and intra-aortic balloon pump support, all guided by real-time echocardiography and CT‑angiography.
✔ Comprehensive Surgical Solutions – The team performs over 2,000 complex adult cardiac surgeries per year, including heart transplants and ventricular assist device implants under the leadership of Professor Pascal Leprince and colleagues.
✔ Integrated Care Pathways – From emergency care to postoperative rehabilitation, patients benefit from bundled support: anesthesia, critical care, physiotherapy, and cardiac rehab programs.
✔ Research-Driven Excellence – Affiliated with the Institute of Cardiometabolism & Nutrition (ICAN) and Sorbonne University, the department participates in early-phase trials and translational research targeting heart failure, metabolic cardiomyopathies, and next-gen imaging biomarkers.
Combining life-saving cardiac surgery with groundbreaking diagnostics and post-surgical care, Pitié‑Salpêtrière delivers world-class solutions in cardiovascular medicine at the crossroads of innovation and compassion.

Dental Treatment at Hôpital Pitié‑Salpêtrière
Hôpital Pitié‑Salpêtrière’s Oral Medicine and Dentofacial Surgery Service is a leading Hospital-University department specializing in comprehensive dental and oral health care. Staffed by experts in oral surgery, implantology, orthodontics, endodontics, and periodontology, the unit serves adult and complex-case patients, including oncology, chronic pain, rare diseases, and individuals with special needs. Emergency oral care is available 24/7, and a dedicated access program ensures that patients from disadvantaged backgrounds receive timely treatment.
✔ Advanced Diagnostics & Emergency Response – Utilizing sophisticated evaluation tools, the department handles urgent dental extractions, chronic oral pain, mucosal disorders, osteonecrosis, and cancer-related consultations. The on-site team ensures seamless referrals for patients in oncology or immunocompromised states.
✔ Comprehensive Oral & Maxillofacial Surgery – The unit manages pre-implant bone reconstruction, wisdom tooth extraction, orthognathic correction, and facial tumor cases. Under expert leadership (Pr. Géraldine Lescaille, Dr. Rafael‑Antonio Toledo Arenas), surgeries range from day care under local or conscious sedation to full general anesthesia.
✔ Interdisciplinary Care Pathways – Collaborations with oncology, ENT, endocrinology, and rehabilitation services support holistic patient journeys from diagnosis to postoperative follow-up. Dental care is seamlessly integrated into broader treatment plans.
✔ Teaching & Research Excellence – As a hospital-university service, it combines high-level clinical activity with active research in rare oral diseases, pain management, and digital dentistry. It also offers advanced training and doctoral programs in stomatology and maxillofacial surgery.
Blending high-quality oral surgery with teaching, research, and compassionate care, Hôpital Pitié‑Salpêtrière delivers outstanding dental treatment in a multidisciplinary, academic environment.

General Surgery at Hôpital Pitié‑Salpêtrière
Hôpital Pitié‑Salpêtrière is internationally recognized for its excellence in general and digestive surgery, offering high-precision procedures for complex abdominal and gastrointestinal conditions. The department is led by leading surgeons and professors who specialize in both open and minimally invasive laparoscopic techniques. The surgical unit works in close collaboration with oncology, gastroenterology, radiology, and critical care departments, ensuring seamless multidisciplinary management, especially for cancer and transplant cases.
✔ Advanced Minimally Invasive Surgery – Laparoscopic and robotic-assisted procedures are routinely used for gallbladder removal, hernia repair, colorectal surgery, bariatric surgery, and liver resections. These methods reduce recovery time, scarring, and postoperative pain.
✔ Multidisciplinary Cancer Surgery – The unit performs complex oncologic surgeries including pancreaticoduodenectomy (Whipple), liver metastasectomy, and esophagectomy. Treatment planning is coordinated with the onco-hematology and digestive oncology teams to optimize outcomes.
✔ Hepatobiliary and Pancreatic Expertise – Recognized for its high-volume experience in liver and pancreatic surgery, the department also provides emergency interventions for hepatic trauma and bile duct injuries.
✔ Transplant & Emergency Surgery – As part of a national transplant center, the hospital offers surgical expertise in liver and kidney transplantation, alongside 24/7 surgical emergency services for trauma, acute appendicitis, and perforations.
✔ Research & Academic Leadership – The department contributes to national and EU-funded clinical trials and trains surgical fellows in advanced techniques and integrated perioperative care.
With a focus on innovation, precision, and safety, general surgery at Hôpital Pitié‑Salpêtrière provides top-tier surgical care supported by one of France’s most advanced academic hospital ecosystems.

Neurology at Hôpital Pitié‑Salpêtrière
Hôpital Pitié‑Salpêtrière is globally recognized for its Neurology Department, historically linked to Jean-Martin Charcot, the father of modern neurology. Today, it remains a world leader in the diagnosis, treatment, and research of neurological disorders. The hospital’s affiliation with Sorbonne University and Inserm fosters a pioneering environment for both clinical excellence and neuroscientific discovery. It offers multidisciplinary expertise in complex pathologies, making it a referral hub for neurological diseases across Europe.
✔ Comprehensive Neurological Diagnostics – The department integrates high-resolution MRI, functional neuroimaging, EEG, and advanced neurophysiology labs for accurate assessment of brain and nervous system conditions.
✔ Specialized Units for Complex Disorders – Subspecialty centers cover a wide range of neurological diseases, including multiple sclerosis, epilepsy, Parkinson’s disease, ALS, neuromuscular disorders, stroke, and neuroinflammatory syndromes.
✔ Advanced Epilepsy & Movement Disorder Clinics – With advanced neurostimulation, deep brain stimulation (DBS), and epilepsy surgery programs, the hospital provides life-changing interventions for drug-resistant conditions.
✔ Neurocritical & Stroke Care – A dedicated neuro-intensive care unit and fast-response stroke center offer emergency neurological care supported by rapid imaging and interventional neuroradiology.
✔ Translational Research & Innovation – Hôpital Pitié‑Salpêtrière plays a central role in neurological research, contributing to breakthroughs in neurodegeneration, cognitive disorders, and neuroimmunology through collaborations with global academic networks.
With its heritage of innovation and excellence, Neurology at Hôpital Pitié‑Salpêtrière represents the forefront of brain and nervous system care in Europe, offering specialized treatment, groundbreaking research, and hope for patients with the most complex neurological conditions.

Onco-Hematology at Hôpital Pitié‑Salpêtrière
The Onco-Hematology Department at Hôpital Pitié‑Salpêtrière is one of France’s foremost centers for the diagnosis and treatment of blood cancers and related malignancies. Affiliated with Sorbonne University and the AP‑HP network, the unit delivers advanced care for conditions such as leukemia, lymphoma, myeloma, and myelodysplastic syndromes. It is supported by advanced laboratories in molecular biology, cytogenetics, and immunology, enabling precise diagnostics and targeted therapy planning.
✔ Comprehensive Cancer Diagnostics – The department utilizes genomic sequencing, flow cytometry, and cytogenetic profiling to accurately subtype hematological cancers, enabling personalized treatment regimens.
✔ Stem Cell & Bone Marrow Transplantation – As a national reference center, the hospital performs autologous and allogeneic hematopoietic stem cell transplants, including matched sibling and unrelated donor procedures, with advanced graft-versus-host disease (GVHD) management.
✔ Targeted Therapies & Immunotherapy – Patients benefit from novel therapies such as CAR-T cell therapy, monoclonal antibodies, and small-molecule inhibitors. The unit is deeply involved in clinical research and trials for next-generation treatments.
✔ Integrated Supportive Care – Multidisciplinary teams provide comprehensive care, including hematology nursing, psycho-oncology, infectious disease management, and nutritional support to improve patient well-being throughout treatment.
✔ Academic & Clinical Research Leadership – The department contributes significantly to European cooperative studies in hematologic oncology and hosts clinical trials through its affiliation with Inserm and AP‑HP research platforms.
By combining academic excellence with compassionate care and therapeutic innovation, Onco-Hematology at Hôpital Pitié‑Salpêtrière stands as a leading destination in Europe for complex blood cancer management and stem cell transplantation.

Oncology at Hôpital Pitié‑Salpêtrière
The Oncology Department at Hôpital Pitié‑Salpêtrière is one of France’s most advanced cancer centers, offering comprehensive, patient-focused cancer care across all major tumor types. As part of the AP‑HP university hospital network and affiliated with Sorbonne University, the hospital integrates clinical treatment with groundbreaking oncology research. Its multidisciplinary model ensures every patient benefits from a personalized treatment plan combining precision diagnostics, targeted therapy, and supportive care.
✔ Organ-Specific Oncology Expertise – The department includes dedicated teams for breast, lung, colorectal, urologic, gynecologic, and head and neck cancers, supported by specialists in surgical oncology, medical oncology, and radiation therapy.
✔ Advanced Imaging & Molecular Diagnosis – Advanced PET-CT, MRI, and genomic profiling allow for accurate staging and molecular characterization, critical for selecting personalized therapies.
✔ Innovative Therapeutic Approaches – Access to clinical trials, immunotherapy, CAR-T cell therapy, and the latest targeted treatments puts patients at the forefront of global cancer innovation.
✔ Oncologic Surgery & Interventional Radiology – Complex tumor resections and minimally invasive techniques are performed by highly trained surgeons in collaboration with interventional radiologists to optimize outcomes.
✔ Supportive & Palliative Oncology – Comprehensive psychosocial support, nutrition, pain management, and palliative care services ensure patients receive holistic attention throughout their treatment journey.
Uniting clinical rigor with compassionate care, Oncology at Hôpital Pitié‑Salpêtrière stands as a reference center for complex cancer cases in Europe, offering hope through innovation, multidisciplinary expertise, and access to the most advanced therapies available.

Ophthalmology at Hôpital Pitié‑Salpêtrière
The Ophthalmology Department at Hôpital Pitié‑Salpêtrière is recognized as one of the top eye care and vision research centers in France. As part of the AP‑HP network and Sorbonne University, the department treats a wide range of ocular conditions, ranging from routine vision problems to complex retinal and neuro-ophthalmological disorders. Equipped with advanced diagnostics and therapeutic technologies, the unit serves as a referral center for rare and difficult eye pathologies.
✔ Retinal & Macular Disease Management – The hospital offers expert care for age-related macular degeneration (AMD), diabetic retinopathy, and retinal detachment, utilizing OCT imaging, retinal angiography, and intravitreal injections.
✔ Corneal & Anterior Segment Surgery – Treatments include corneal transplants, keratoconus care, refractive surgery (LASIK/PRK), and advanced cataract surgery using femtosecond lasers and premium lenses.
✔ Neuro-Ophthalmology & Rare Eye Disorders – As a university hospital with neurology expertise, the department leads in diagnosing and treating visual problems linked to neurological diseases such as multiple sclerosis and optic neuritis.
✔ Pediatric & Strabismus Care – Specialized pediatric ophthalmologists manage vision development, amblyopia, and ocular misalignment in children, using gentle, tailored treatment protocols.
✔ Glaucoma & Intraocular Pressure Management – Minimally invasive glaucoma surgeries (MIGS), laser treatments, and individualized pharmacologic plans are offered to preserve vision and prevent progression.
Focusing on clinical excellence, innovative research, and patient education, Ophthalmology at Hôpital Pitié‑Salpêtrière delivers highly specialized care that attracts patients nationally and internationally for both routine and rare eye conditions.

Orthopedics at Hôpital Pitié‑Salpêtrière
The Orthopedics and Traumatology Department at Hôpital Pitié‑Salpêtrière is a renowned center for musculoskeletal surgery and rehabilitation in France. As part of a university hospital and teaching institution, it provides high-level orthopedic care for complex trauma, degenerative joint conditions, and spine pathologies. The department specializes in advanced surgical interventions supported by advanced imaging, robotic assistance, and a multidisciplinary rehabilitation framework.
✔ Joint Replacement & Arthroplasty – The hospital performs high volumes of hip, knee, and shoulder replacements using minimally invasive and computer-assisted techniques. Customized implants and rapid recovery protocols improve mobility and reduce hospital stay.
✔ Sports Injury & Arthroscopic Surgery – Experts manage ligament injuries, meniscal tears, tendon ruptures, and cartilage repair using minimally invasive arthroscopy for faster healing and reduced downtime.
✔ Trauma & Fracture Management – The trauma unit handles complex fractures, polytrauma cases, and osteoporotic fractures with 24/7 emergency surgical coverage and post-op functional rehab.
✔ Spine & Deformity Surgery – In collaboration with neurosurgery and rehabilitation, the orthopedic spine team treats scoliosis, herniated discs, spinal stenosis, and vertebral fractures through minimally invasive and open techniques.
✔ Pediatric & Congenital Orthopedics – Specialized care is offered for congenital limb deformities, hip dysplasia, clubfoot, and growth-related orthopedic issues in children and adolescents.
Blending surgical innovation with coordinated rehabilitation and follow-up, the Orthopedics Department at Hôpital Pitié‑Salpêtrière delivers safe, effective, and personalized treatment for both common and complex musculoskeletal conditions.

Plastic Surgery at Hôpital Pitié‑Salpêtrière
The Plastic, Reconstructive, and Aesthetic Surgery Department at Hôpital Pitié‑Salpêtrière is a leading center for complex reconstructive procedures, oncologic reconstruction, and selected aesthetic surgeries. Integrated within one of Europe’s top university hospitals, the department emphasizes both functional restoration and refined cosmetic outcomes. Its surgeons are internationally recognized for their expertise in microsurgery, facial reconstruction, and post-cancer breast reconstruction.
✔ Oncologic Reconstruction – Specializing in breast reconstruction post-mastectomy, head and neck tumor resections, and skin cancer surgeries, offering flap techniques, prosthesis-based solutions, and regenerative procedures.
✔ Microsurgery & Complex Wound Repair – The team excels in delicate microsurgical interventions for trauma, diabetic wounds, pressure sores, and soft-tissue defects, ensuring optimal function and appearance.
✔ Craniofacial & Facial Surgery – Reconstructive care for congenital deformities, facial fractures, and post-tumor resections is combined with aesthetic refinements for facial harmony and recovery.
✔ Hand & Nerve Surgery – Collaboration with neurology and orthopedics enables treatment of hand trauma, peripheral nerve injuries, and congenital hand anomalies through reconstructive and nerve repair techniques.
✔ Selective Aesthetic Procedures – While the focus remains on medical plastic surgery, the unit performs select aesthetic procedures, including eyelid surgery (blepharoplasty), otoplasty, and scar revision, primarily for post-trauma or post-cancer patients.
Combining surgical artistry with clinical precision, the Plastic Surgery Department at Hôpital Pitié‑Salpêtrière ensures every intervention supports both function and form. Its multidisciplinary support structure makes it a national referral center for advanced reconstructive needs.

Reproductive Medicine at Hôpital Pitié‑Salpêtrière
The Reproductive Medicine and Fertility Unit at Hôpital Pitié‑Salpêtrière is one of France’s most prominent centers for assisted reproductive technologies (ART) and the management of complex infertility cases. Equipped with advanced laboratories and staffed by expert gynecologists, endocrinologists, embryologists, and psychologists, the unit offers a full spectrum of diagnostic and therapeutic fertility services for individuals and couples. The department is committed to ethical, evidence-based care and is part of AP-HP’s coordinated reproductive health network.
✔ Advanced Fertility Treatments – Services include ovulation induction, intrauterine insemination (IUI), in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and fertility preservation through egg or sperm freezing.
✔ Fertility Preservation & Oncofertility – The unit works in close coordination with oncology teams to preserve reproductive potential in cancer patients through gamete cryopreservation and embryo freezing before treatment.
✔ Hormonal & Endocrine Evaluation – A thorough investigation of hormonal imbalances, polycystic ovary syndrome (PCOS), premature ovarian failure, and male factor infertility ensures personalized treatment planning.
✔ Recurrent Miscarriage & Implantation Failure – Specialized protocols are available for women facing repeated pregnancy loss or unsuccessful implantation, integrating genetic screening and uterine assessment.
✔ Ethical Support & Psychological Counseling – The team provides psychological guidance throughout treatment, respecting patient autonomy, anonymity regulations, and ethical frameworks within French reproductive law.
With its combination of medical excellence, innovation, and compassionate support, the Reproductive Medicine Unit at Hôpital Pitié‑Salpêtrière remains at the forefront of fertility care in France. It is especially recognized for handling complex or medically sensitive fertility cases with discretion and success.

Spine Surgery at Hôpital Pitié‑Salpêtrière
The Spine Surgery Unit at Hôpital Pitié‑Salpêtrière is a nationally recognized center for advanced spinal care, offering both surgical and non-surgical treatments for a wide spectrum of spinal disorders. The unit treats degenerative, traumatic, tumoral, infectious, and congenital spine conditions with a multidisciplinary team of orthopedic surgeons, neurosurgeons, radiologists, anesthesiologists, and rehabilitation specialists. With access to high-precision imaging and advanced operating theaters, the department is known for managing complex spinal pathologies and revision cases with high success rates.
✔ Minimally Invasive Spine Surgery (MISS) – The department utilizes endoscopic and microsurgical techniques to reduce tissue trauma, speed up recovery, and minimize hospital stays, especially in lumbar disc herniation and spinal stenosis cases.
✔ Complex Spine Reconstruction – Specializing in treating spinal deformities, failed back surgeries, and vertebral instability through custom instrumentation, spinal fusion, and vertebral body replacement.
✔ Spinal Tumors & Oncologic Resection – Collaboration with neuro-oncology and radiotherapy teams enables safe resection of primary and metastatic spinal tumors with intraoperative neuromonitoring.
✔ Degenerative Disc Disease & Spondylolisthesis – Advanced treatments include dynamic stabilization systems, total disc replacement, and decompression techniques tailored to the patient’s anatomy and activity level.
✔ Multidisciplinary Spine Unit – Integrated patient care involves neurologists, pain specialists, physiatrists, and physical therapists to ensure comprehensive pre- and post-operative rehabilitation and long-term mobility outcomes.
Spine Surgery at Hôpital Pitié‑Salpêtrière is defined by clinical precision, innovation, and a patient-first approach. Its reputation for treating highly complex spinal disorders draws referrals from across France and Europe, making it one of the top spinal surgery units within the AP-HP network.
